MDMA is well known for its effects on serotonin release, but the downside is that it also creates oxidative stress in the brain. When serotonin and dopamine surge, free radicals are generated at a higher rate than normal. Over time, this oxidative stress is thought to contribute to MDMA-related neurotoxicity.
How Vitamin C Helps
Vitamin C is a powerful antioxidant. Research has shown that it can help reduce the oxidative stress caused by MDMA:
- In one study, giving Vitamin C five hours after MDMA administration preserved ATP and serotonin function, protecting key parts of the brain. (PubMed)
- Another study demonstrated that Vitamin C prevented the formation of harmful hydroxyl radicals and reduced MDMA’s typical serotonin depletion and behavioral changes. (PubMed)
Together, these findings suggest that Vitamin C can play an important role in protecting the brain against MDMA-induced damage.
Ascorbic Acid vs Calcium Carbonate
Some people find taking vitamin C under the form of Ascorbic Acid to reduce the MDMA high, since MDMA is an amphetamine, it is basic by nature, so taking an acid will do an acid base neutralization, reducing the amount of MDMA your body actually absorbs. This is where the form of Vitamin C as Calcium Carbonate comes into play; it is also a base. Which means it does not destroy any of your MDMA taken, and making sure you don’t accidentally undermine your buzz by protecting yourself . This is how we difference ourselves from the other supplement companies, since they only use the cheapest version of Vitamin C. By putting Calcium Carbonate in our stack, we ensure that you get protection with your high, not instead.
TLDR
Many people choose to supplement with Vitamin C both before and after MDMA use to help strengthen the brain’s natural antioxidant defenses. But not all forms are equal — some can dull your high. That’s why we use the one that protects your brain and preserves your roll..
So What Should I Do?
The Afterglow Pack provides a complete blend of antioxidants and minerals designed to support your body during and after MDMA use. Ingredients like Vitamin C, NAC, and Alpha Lipoic Acid work together to counter oxidative stress, while Magnesium and Melatonin help restore balance and promote quality sleep.
By combining these supplements, the Afterglow Pack supports serotonin recovery, reduces comedown intensity, and helps you feel more balanced in the days after.
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